Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23565938 | 0.65 | MEN1 (0.37) | — | |
| SCHEMBL13384404 | 0.63 | MAPK1 (0.35) | LMNA | |
| SCHEMBL18595554 | 0.62 | ALDH1A1 (0.32) | KDM4EHPGD | |
| SCHEMBL12285120 | 0.62 | TSHR (0.35) | LMNA | |
| SCHEMBL23566057 | 0.62 | PDE1A (0.50) | — | |
| SCHEMBL14116468 | 0.61 | KDM4E (0.32) | KDM4E | |
| SCHEMBL19497078 | 0.60 | KDM4E (0.37) | PTGER4KDM4ELMNAL3MBTL1 | |
| SCHEMBL10235431 | 0.60 | CYP11B2 (0.36) | — | |
| SCHEMBL5050711 | 0.59 | PTGER4 (0.35) | PTGER4KDM4ELMNA | |
| SCHEMBL10022436 | 0.59 | BRPF1 (0.44) | PTGER4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247770-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海璎黎药业有限公司 | 2022-12-01 | — | — | WO | disclosed |