Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005542 | 0.73 | SRD5A2 (0.35) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL3623734 | 0.70 | TSHR (0.39) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL2299169 | 0.67 | ALDH1A1 (0.34) | TSHRLMNA | |
| SCHEMBL23299696 | 0.67 | TSHR (0.37) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL23299694 | 0.66 | OAT (0.46) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL417350 | 0.65 | OAT (0.37) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL6641316 | 0.65 | OAT (0.37) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL23274778 | 0.65 | OAT (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL23274780 | 0.65 | OAT (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL23299700 | 0.63 | OAT (0.43) | GABRPGABRDGABRA1TSHRGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| EP-4301724-A1 | (S)-3-AMINO-4,4-DIHALOCYCLOPENT-1-ENECARBOXYLIC ACID AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE | Northwestern University (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187523-A1 | (S)-3-AMINO-4,4-DIHALOCYCLOPENT-1-ENECARBOXYLIC ACID AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2022-09-09 | — | — | WO | disclosed |
| WO-2022187523-A1 | (S)-3-AMINO-4,4-DIHALOCYCLOPENT-1-ENECARBOXYLIC ACID AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE | NORTHWESTERN UNIVERSITY (US) | 2022-09-09 | — | — | WO | disclosed |