Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473203 | 1.00 | GRIK1 (0.40) | GRIK1GRIK2GRIK3TDP1MGLL | |
| SCHEMBL2672425 | 0.83 | PAM (0.39) | TDP1MGLLMEN1KMT2ACYSLTR2 | |
| SCHEMBL2672426 | 0.83 | PAM (0.39) | TDP1MGLLMEN1KMT2ACYSLTR2 | |
| SCHEMBL2474133 | 0.83 | MGLL (0.39) | TDP1MGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL2474137 | 0.83 | MGLL (0.39) | TDP1MGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL2672423 | 0.83 | PAM (0.39) | TDP1MGLLMEN1KMT2ACYSLTR2 | |
| SCHEMBL2474129 | 0.81 | CYP2C19 (0.42) | TDP1MGLLALDH1A1 | |
| SCHEMBL2673179 | 0.81 | CYSLTR2 (0.43) | TDP1MGLLCYSLTR2CYSLTR1 | |
| SCHEMBL2673178 | 0.81 | CYSLTR2 (0.43) | TDP1MGLLCYSLTR2CYSLTR1 | |
| SCHEMBL2673173 | 0.81 | CYSLTR2 (0.43) | TDP1MGLLCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |