Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474137 | 1.00 | MGLL (0.39) | MGLLTDP1ALDH1A1GLAMEN1 | |
| SCHEMBL2672634 | 0.85 | MGLL (0.43) | MGLLTDP1ALDH1A1PTGER1PTGER4 | |
| SCHEMBL2672628 | 0.85 | MGLL (0.43) | MGLLTDP1ALDH1A1PTGER1PTGER4 | |
| SCHEMBL2672639 | 0.85 | MGLL (0.43) | MGLLTDP1ALDH1A1PTGER1PTGER4 | |
| SCHEMBL2672425 | 0.83 | PAM (0.39) | MGLLTDP1MEN1KMT2A | |
| SCHEMBL2672426 | 0.83 | PAM (0.39) | MGLLTDP1MEN1KMT2A | |
| SCHEMBL2672423 | 0.83 | PAM (0.39) | MGLLTDP1MEN1KMT2A | |
| SCHEMBL2473203 | 0.83 | GRIK1 (0.40) | MGLLTDP1ALDH1A1GLAMEN1 | |
| SCHEMBL2473204 | 0.83 | GRIK1 (0.40) | MGLLTDP1ALDH1A1GLAMEN1 | |
| SCHEMBL2673179 | 0.81 | CYSLTR2 (0.43) | MGLLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |