SCHEMBL24732276

SCHEMBL24732276

CC(C)c1cccc(C(C)C)c1N(C(C)C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRB2 P47870 2/20 0.41
CYP3A4 P08684 2/20 0.41
FAAH O00519 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
GABRB1 P18505 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
HTR2B P41595 1/20 0.41
GABRA2 P47869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433566 0.78 GABRA1 (0.44) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL17576285 0.77 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL24732272 0.77 CYP1A2 (0.33) GABRA1GABRB2CYP3A4CA1CA2
SCHEMBL10170026 0.73 GABRA1 (0.48) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL22705066 0.71 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL59823 0.70 GABRA1 (0.50) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL14306335 0.70 GABRA1 (0.50) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL21120530 0.69 GABRA1 (0.40) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL8608048 0.69 GABRA1 (0.48) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL14236878 0.69 GABRA1 (0.48) GABRA1GABRG2GABRB3GABRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed
US-20220302395-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 GABRA1 3664/4885GABRG2 3793/4885GABRB3 3282/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 GABRA1 3596/4885GABRG2 4073/4885GABRB3 3066/4885
US-20220302395-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 GABRA1 3664/4885GABRG2 3793/4885GABRB3 3282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.