SCHEMBL17576285

SCHEMBL17576285

CC(C)c1cccc(C(C)C)c1N(C)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.43
GABRG2 P18507 2/20 0.43
GABRB3 P28472 2/20 0.43
GABRB2 P47870 2/20 0.43
CYP3A4 P08684 2/20 0.43
LMNA P02545 2/20 0.43
FAAH O00519 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
GABRB1 P18505 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2C P28335 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
HTR2B P41595 1/20 0.43
GABRA2 P47869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21120530 0.83 GABRA1 (0.40) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL17576281 0.80 GABRA1 (0.38) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL24433566 0.80 GABRA1 (0.44) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL20878137 0.77 MEN1 (0.33) KMT2A
SCHEMBL24732276 0.77 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL59823 0.77 GABRA1 (0.50) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL22186166 0.75 GABRA1 (0.37) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL21040956 0.74 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL22705066 0.73 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2CYP3A4
SCHEMBL30154737 0.72 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11700765-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-20200185625-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 US disclosed
US-10636983-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-04-28 US disclosed
US-10403830-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
US-20190207128-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-07-04 US disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed
US-10301338-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-28 US disclosed
US-10256419-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-09 US disclosed
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-03-29 US disclosed
US-20170162802-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-08 US disclosed
US-20170162802-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-08 US disclosed
EP-3091024-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-11-09 EP disclosed
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-10 US disclosed
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744142-B2 Organic electroluminescent materials and devices TLL1, TLL2, ALPL GABRA1 3043/4885GABRG2 3698/4885GABRB3 3270/4885
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 GABRA1 2476/4885GABRG2 2279/4885GABRB3 2692/4885
US-20170162802-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, KCNQ2 GABRA1 4605/4885GABRG2 4494/4885GABRB3 4573/4885
US-20200185625-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EML4 GABRA1 3811/4885GABRG2 3708/4885GABRB3 3727/4885
US-20190207128-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 GABRA1 2476/4885GABRG2 2279/4885GABRB3 2692/4885
US-10256419-B2 Organic electroluminescent materials and devices EML4, TYR, CPNE4 GABRA1 2476/4885GABRG2 2279/4885GABRB3 2692/4885
US-10636983-B2 Organic electroluminescent materials and devices EML4, TYR, CPNE4 GABRA1 2476/4885GABRG2 2279/4885GABRB3 2692/4885
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 GABRA1 2476/4885GABRG2 2279/4885GABRB3 2692/4885
US-11700765-B2 Organic electroluminescent materials and devices SOD1, L1CAM, MCM2 GABRA1 3760/4885GABRG2 2574/4885GABRB3 2896/4885
US-10403830-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, KCNQ2 GABRA1 4605/4885GABRG2 4494/4885GABRB3 4573/4885
US-10301338-B2 Organic electroluminescent materials and devices PNMT, TAAR5, TST GABRA1 571/4885GABRG2 1417/4885GABRB3 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.