SCHEMBL24733266

SCHEMBL24733266

Cc1cccc2c1-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1c(C)cccc41)-c1cccc(C)c1-3)c1c(C)cccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.38
CLK4 Q9HAZ1 5/20 0.38
CYP3A4 P08684 5/20 0.38
CYP2D6 P10635 4/20 0.38
HSD17B10 Q99714 4/20 0.38
CYP2C19 P33261 2/20 0.38
ALOX15 P16050 2/20 0.38
USP2 O75604 1/20 0.38
TSHR P16473 3/20 0.35
MAPK1 P28482 2/20 0.35
ALDH1A1 P00352 2/20 0.35
REN P00797 1/20 0.35
PARP14 Q460N5 1/20 0.34
LMNA P02545 2/20 0.34
ADORA2A P29274 1/20 0.34
HPGD P15428 1/20 0.33
HSP90AA1 P07900 1/20 0.33
TYMS P04818 1/20 0.33
AHR P35869 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3421160 0.88 CYP1A2 (0.43) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL3419882 0.87 CYP1A2 (0.42) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL2882792 0.87 CYP1A2 (0.42) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL11786632 0.85 CYP1A2 (0.35) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL8077079 0.84 CYP1A2 (0.34) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL13464453 0.79 AURKA (0.33) CYP1A2CYP3A4HSD17B10USP2TSHR
SCHEMBL8742321 0.77
SCHEMBL10330637 0.77 TDP1 (0.39) CYP1A2CLK4CYP3A4CYP2D6HSD17B10
SCHEMBL8997093 0.77 PTGES (0.36) CYP1A2CYP3A4CYP2C19MAPK1ALDH1A1
SCHEMBL12200945 0.77 CDK4 (0.37) CYP1A2CYP2D6HSD17B10CYP2C19ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022255135-A1 PHTHALOCYANINE COMPOUND DIC株式会社 2022-12-08 WO disclosed