⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476852 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4699794 | 0.98 | — | — | |
| SCHEMBL3597923 | 0.88 | DGAT1 (0.34) | — | |
| SCHEMBL3595127 | 0.88 | IDO1 (0.32) | — | |
| SCHEMBL3599238 | 0.88 | ALOX5 (0.33) | — | |
| SCHEMBL3602073 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3604458 | 0.85 | POLB (0.30) | — | |
| SCHEMBL8713361 | 0.84 | LPL (0.35) | — | |
| SCHEMBL8713810 | 0.81 | LPL (0.39) | — | |
| SCHEMBL3606206 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346988-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2008-11-12 | — | — | EP | claimed |
| US-6878831-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-04-12 | — | — | US | claimed |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | claimed |
| EP-1346988-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-09-24 | — | — | EP | claimed |
| EP-1637527-B1 | CANNABINOID RECEPTOR MODULATOR | TAKEDA PHARMACEUTICAL (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-1411052-B1 | BENZO-FUSED 5-MEMBERED HETROCYCLE COMPOUNDS,PROCESS FOR PREPARATION OF THE SAME, AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20100273852-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100240743-A1 | CANNABINOID RECEPTOR MODULATOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100056505-A1 | Substituted Pyrazalones | BIOGEN IDEC MA INC. | 2010-03-04 | — | — | US | disclosed |
| EP-2079455-B1 | PHARMACEUTICAL COMPOSITION COMPRISING A DIHYDROBENZOFURANYL ISOINDOLINE AND A LIPOPHILIC COMPONENT | TAKEDA PHARMACEUTICAL (JP) | 2010-01-27 | — | — | EP | disclosed |
| EP-2079455-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A DIHYDROBENZOFURANYL ISOINDOLINE AND A LIPOPHILIC COMPONENT | Takeda Pharmaceutical Company Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7521545-B2 | Azo compounds and process for production thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20020160996-A1 | Benzofuran derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1136477-A1 | BENZOFURAN DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-5770772-A | 4-FORMYLAMINO-2,3,5-TRIMETHYL-1-(2-METHYL-2-PROPENYLOXY) -BENZENE; ARTERIOSCLEROSIS, BRAIN AND CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5594154-A | 5-AMINO-2-BROMOMETHYL-2,4,6,7-TETRAMETHYL-2,3-DIHYDROBENZO(B) FURANS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5478844-A | Method of using aminocoumaran derivatives for treating cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0483772-A1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |