Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474121 | 0.83 | TAAR1 (0.58) | BRD4TAAR1MAPTGAAALDH1A1 | |
| SCHEMBL2468823 | 0.76 | BRD4 (0.52) | BRD4TAAR1MAPTGAAMAPK1 | |
| SCHEMBL3171290 | 0.75 | TAAR1 (0.61) | BRD4TAAR1MAPTGAAALDH1A1 | |
| SCHEMBL3165410 | 0.75 | TAAR1 (0.61) | BRD4TAAR1MAPTGAAHSD17B10 | |
| SCHEMBL2471212 | 0.75 | TAAR1 (0.56) | BRD4TAAR1MAPTGAAALDH1A1 | |
| SCHEMBL2469606 | 0.75 | TAAR1 (0.56) | BRD4TAAR1MAPTGAATP53 | |
| SCHEMBL3164870 | 0.74 | TAAR1 (0.56) | BRD4TAAR1MAPTGAAMAPK1 | |
| SCHEMBL6297836 | 0.74 | BRD4 (0.50) | BRD4TAAR1MAPTALDH1A1KLK1 | |
| SCHEMBL2776944 | 0.73 | TAAR1 (0.68) | BRD4TAAR1MAPTGAAALDH1A1 | |
| SCHEMBL10885778 | 0.73 | TP53 (0.47) | MAPTGAATP53MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10485786-B2 | Pharmaceutical composition for preventing or treating macular degeneration | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2019-11-26 | — | — | US | disclosed |
| US-20180221343-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-08-09 | — | — | US | disclosed |
| EP-2692345-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | KOREA RES INST CHEMICAL TECH (KR) | 2017-07-19 | — | — | EP | disclosed |
| EP-2692345-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | Korea Research Institute Of Chemical Technology (KR) | 2014-02-05 | — | — | EP | disclosed |
| US-20140018402-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | Catholic University Industry Academic Cooperation Foundation (KR) | 2014-01-16 | — | — | US | disclosed |
| EP-1546136-B1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RES INST CHEM TECH (KR) | 2011-10-05 | — | — | EP | disclosed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| EP-1879455-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | Bayer CropScience AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| US-7279497-B2 | Benzopyran derivatives substituted with secondary amines including imidazole, their preparation and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-10-09 | — | — | US | disclosed |
| EP-1546136-A4 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RES INST CHEM TECH (KR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2006119411-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-11-09 | — | — | WO | disclosed |
| US-20050267188-A1 | Therapy of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, for protection of heart, neuronal cells, brain injury, organs for preservation or in cardiovascular surgery against ischemia-reperfusion injury or oxidative stress | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-12-01 | — | — | US | disclosed |
| EP-1546136-A1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Korea Research Institute of Chemical Technology (KR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014898-A1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018402-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | PDE6D, PDE6C, PDE6G | BRD4 952/4885TAAR1 1079/4885MAPT 442/4885 |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | DDT, AADAC, DDC | BRD4 4006/4885TAAR1 162/4885MAPT 4853/4885 |
| US-10485786-B2 | Pharmaceutical composition for preventing or treating macular degeneration | PDE6D, PDE6C, PDE6G | BRD4 952/4885TAAR1 1079/4885MAPT 442/4885 |
| US-20180221343-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MACULAR DEGENERATION | PDE6D, PDE6C, PDE6G | BRD4 952/4885TAAR1 1079/4885MAPT 442/4885 |
| US-20050267188-A1 | Therapy of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, for protection of heart, neuronal cells, brain injury, organs for preservation or in cardiovascular surgery against ischemia-reperfusion injury or oxidative stress | FLT4, ALDH1A2, KDR | BRD4 326/4885TAAR1 4184/4885MAPT 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.