SCHEMBL2473393

SCHEMBL2473393

Oc1ccc(C=CC=Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.73
MAOB P27338 6/20 0.58
CXCL12 P48061 1/20 0.58
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 3/20 0.58
MAPT P10636 3/20 0.58
MAOA P21397 3/20 0.56
HDAC6 Q9UBN7 2/20 0.55
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC9 Q9UKV0 1/20 0.55
HDAC5 Q9UQL6 1/20 0.55
MMP1 P03956 1/20 0.53
MMP2 P08253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8395184 0.90 MAOB (0.62) APPMAOBCXCL12KDM4EALDH1A1
SCHEMBL8395187 0.90 MAOB (0.62) APPMAOBCXCL12KDM4EALDH1A1
SCHEMBL2622607 0.87 HDAC3 (0.59) APPMAOBMAOAHDAC6HDAC3
SCHEMBL5179114 0.87 APP (0.94) APPMAOBKDM4EALDH1A1MAPT
SCHEMBL11439096 0.87 APP (0.94) APPMAOBKDM4EALDH1A1MAPT
SCHEMBL11451994 0.87 HDAC3 (0.59) APPMAOBMAOAHDAC6HDAC3
SCHEMBL2829008 0.85 APP (1.00) APPMAOBKDM4EALDH1A1MAPT
SCHEMBL21798645 0.85 APP (1.00) APPMAOBKDM4EALDH1A1MAPT
SCHEMBL18417175 0.85 HDAC3 (0.57) APPMAOBMAOAHDAC6HDAC3
Parachlorophenol SCHEMBL10549360 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2370859-A2 A PHOTOSENSITIVE COMPOSITION AZ Electronic Materials USA Corp. (US) 2011-10-05 EP disclosed
WO-2010064135-A2 A PHOTOSENSITIVE COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-06-10 WO disclosed
US-20100136477-A1 Photosensitive Composition AZ ELECTRONIC MATERIALS USA CORP. 2010-06-03 US disclosed
EP-2111567-A2 PHOTORESIST COMPOSITION AZ Electronic Materials USA Corp. (US) 2009-10-28 EP disclosed
WO-2008096263-A2 PHOTORESIST COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-08-14 WO disclosed
US-20080187868-A1 Photoactive Compounds AZ ELECTRONIC MATERIALS USA CORP. 2008-08-07 US disclosed
US-5350660-A Chemical amplified resist material containing photosensitive compound capable of generating an acid and specific polystyrene copolymer having functional groups that become alkali-soluble under an acid atmosphere WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1994-09-27 US disclosed
EP-0440374-A2 Chemical amplified resist material WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1991-08-07 EP disclosed