SCHEMBL8395187

SCHEMBL8395187

Oc1ccc(C=Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.62
CXCL12 P48061 1/20 0.62
APP P05067 6/20 0.58
CYP1A2 P05177 3/20 0.58
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA3 P07451 2/20 0.58
CA4 P22748 2/20 0.58
CA6 P23280 2/20 0.58
CA5A P35218 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA13 Q8N1Q1 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA5B Q9Y2D0 2/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 2/20 0.58
ALDH1A1 P00352 2/20 0.58
LMNA P02545 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8395184 1.00 MAOB (0.62) MAOBCXCL12APPCYP1A2CA12
SCHEMBL2473393 0.90 APP (0.73) MAOBCXCL12APPCYP1A2CA12
Trans-4,4'-Dihydroxystilbene SCHEMBL13339135 0.86 APP (0.74) MAOBAPPCYP1A2CA12CA1
SCHEMBL260347 0.86 AHR (0.74) MAOBCYP1A2KDM4EALDH1A1LMNA
Trans-4,4'-Dihydroxystilbene SCHEMBL145659 0.86 APP (0.74) MAOBAPPCYP1A2CA12CA1
SCHEMBL699666 0.86 AHR (0.74) MAOBCYP1A2KDM4EALDH1A1LMNA
SCHEMBL6266983 0.86 APP (0.74) MAOBAPPCYP1A2CA12CA1
SCHEMBL6266989 0.86 APP (0.74) MAOBAPPCYP1A2CA12CA1
SCHEMBL20582895 0.86 AHR (0.74) MAOBCYP1A2KDM4EALDH1A1LMNA
SCHEMBL9679426 0.86 AHR (0.74) MAOBCYP1A2KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5612479-A Polyphenols containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1997-03-18 US disclosed
US-5470946-A Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1995-11-28 US disclosed
US-5442039-A Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength THE DOW CHEMICAL COMPANY (US) 1995-08-15 US disclosed
US-5428125-A Liquid crystalline THE DOW CHEMICAL COMPANY (US) 1995-06-27 US disclosed
US-5374769-A Polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1994-12-20 US disclosed
EP-0589971-A1 COMPOUNDS SMITHKLINE BEECHAM PLC (GB) 1994-04-06 EP disclosed
US-5248758-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5206321-A Polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
WO-1992022527-A2 3-SUBSTITUTED PYRROLIDINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1992-12-23 WO disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5077380-A Mesogenic cyanate functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-12-31 US disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0391204-A2 Process for preparing moulded articles of polymers with E-configurated stilbene moieties BAYER AG (DE) 1990-10-10 EP disclosed