SCHEMBL2622607

SCHEMBL2622607

Clc1ccc(/C=C/C=C/c2ccc(Cl)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.59
HDAC4 P56524 1/20 0.59
HDAC1 Q13547 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC2 Q92769 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
HDAC9 Q9UKV0 1/20 0.59
HDAC5 Q9UQL6 1/20 0.59
AHR P35869 1/20 0.59
CYP1A2 P05177 1/20 0.54
HSD17B10 Q99714 1/20 0.52
MAOB P27338 5/20 0.50
APP P05067 2/20 0.50
LMNA P02545 1/20 0.50
CYP2A6 P11509 1/20 0.50
FBP1 P09467 1/20 0.50
MAOA P21397 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11451994 1.00 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18417175 0.97 HDAC3 (0.57) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2622613 0.89 MAOB (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2622601 0.89 MAOB (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL137664 0.89 MAOB (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL17390783 0.89 HDAC3 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18416524 0.87 MAOB (0.67) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2473393 0.87 APP (0.73) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2632276 0.87 IDO1 (0.62) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL15759529 0.87 MAOB (0.67) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102708-B1 CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME FUJIFILM CORP (JP) 2018-05-16 EP disclosed
US-9684254-B2 Diamine compound and electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed
US-9684254-B2 Diamine compound and electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed
US-20170031252-A1 DIAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-02-02 US disclosed
US-20170031252-A1 DIAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-02-02 US disclosed
EP-3124467-A1 DIAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER Kyocera Document Solutions Inc. (JP) 2017-02-01 EP disclosed
EP-2037323-B1 Photosensitive compositions FUJIFILM CORP (JP) 2014-12-10 EP disclosed
US-8785087-B2 Pigment-dispersed composition, curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-8785087-B2 Pigment-dispersed composition, curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-8778575-B2 Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
EP-1975702-A2 Colored photocurable composition for solid state image pick-up device, color filter and method for production thereof, and solid state image pick-up device Fujifilm Corporation (JP) 2008-10-01 EP disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
WO-2008081988-A1 CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME FUJIFILM CORPORATION (JP) 2008-07-10 WO disclosed
US-20080076043-A1 CURABLE COMPOSITION, COLOR FILTER AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080076043-A1 CURABLE COMPOSITION, COLOR FILTER AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
EP-1903393-A2 Curable composition, color filter and manufacturing method thereof FUJIFILM Corporation (JP) 2008-03-26 EP disclosed
EP-1847576-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM Corporation (JP) 2007-10-24 EP disclosed
US-20070242120-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed
US-20070242120-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170031252-A1 DIAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AOC1, H1-10, CRY1 HDAC3 2741/4885HDAC4 3840/4885HDAC1 2030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.