Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.71 |
| ▸ | CTSS | P25774 | 4/20 | 0.71 |
| ▸ | CTSB | P07858 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CTSK | P43235 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MME | P08473 | 1/20 | 0.63 |
| ▸ | ECE1 | P42892 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221435 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8837344 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL7264750 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL221434 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8837339 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL5145628 | 1.00 | CTSL (0.71) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL7049933 | 0.95 | CTSB (0.72) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL29576918 | 0.91 | CTSB (0.64) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8662503 | 0.90 | CTSB (0.70) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL8333301 | 0.90 | CTSL (0.70) | CTSLCTSSCTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4086272-A1 | METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-11-09 | — | — | EP | disclosed |