Sugi Predict

Sugi Predict / Compounds / SCHEMBL221434

SCHEMBL221434

SCHEMBL221434

CCC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 4/20 0.71
▸ CTSS P25774 4/20 0.71
▸ CTSB P07858 3/20 0.71
▸ MEN1 O00255 2/20 0.68
▸ KMT2A Q03164 2/20 0.68
▸ LMNA P02545 1/20 0.68
▸ CTSK P43235 5/20 0.65
▸ CYP3A4 P08684 1/20 0.65
▸ CYP2D6 P10635 1/20 0.65
▸ CYP2C9 P11712 1/20 0.65
▸ CYP2C19 P33261 1/20 0.65
▸ RAB9A P51151 1/20 0.65
▸ MME P08473 1/20 0.63
▸ ECE1 P42892 1/20 0.63
▸ CASP3 P42574 2/20 0.58
▸ TYR P14679 1/20 0.55
▸ ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221435 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL8837344 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL7264750 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL8837339 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL5145628 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL24734375 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL7049933 0.95 CTSB (0.72) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL29576918 0.91 CTSB (0.64) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL8662503 0.90 CTSB (0.70) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL8333301 0.90 CTSL (0.70) CTSLCTSSCTSBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 — — CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 — — US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 — — US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 — — US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 — — US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 — — WO claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 — — US disclosed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 — — US disclosed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP disclosed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 — — EP disclosed
WO-1984003088-A1 NEW NITROSOUREAS, PREPARATION METHOD THEREOF AND THEIR APPLICATION IN THERAPY CENTRE NAT RECH SCIENT (FR) 1984-08-16 — — WO disclosed
US-4382142-A ANTITUMOR AND ANTICARCINOGENIC AGENTS; LEUKEMIA KOWA CO., LTD. (JP) 1983-05-03 — — US disclosed
EP-0061768-A1 N-amido substituted dipeptides USV PHARMACEUTICAL CORPORATION (US) 1982-10-06 — — EP disclosed
US-4251529-A CEREBROSIDES SANDOZ LTD. (CH) 1981-02-17 — — US disclosed
US-RE30473-E ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES HOFFMANN-LA ROCHE INC. (US) 1981-01-06 — — US disclosed
US-4105852-A ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES HOFFMANN-LA ROCHE INC. (US) 1978-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP CTSL 1366/4885CTSS 2330/4885CTSB 1304/4885
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS CTSL 1773/4885CTSS 1056/4885CTSB 1530/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC CTSL 1059/4885CTSS 880/4885CTSB 942/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CTSL 1773/4885CTSS 1056/4885CTSB 1530/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CTSL 1811/4885CTSS 3839/4885CTSB 3814/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CTSL 1773/4885CTSS 1056/4885CTSB 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.