SCHEMBL6841703

SCHEMBL6841703

[CH2]C(C)N1CCC(O)CC1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 2/20 0.36
HRH3 Q9Y5N1 1/20 0.34
KCNA3 P22001 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422753 0.79 HRH3 (0.46) GPR119HRH3LMNACYP2C9
SCHEMBL22565324 0.77 GPR119 (0.37) GPR119HRH3LMNACYP2C9TSHR
SCHEMBL27628768 0.77 GPR119 (0.37) GPR119TSHR
SCHEMBL19527522 0.75 GPR119 (0.36) GPR119HRH3LMNACYP2C9TSHR
SCHEMBL23103238 0.75 GPR119 (0.36) GPR119HRH3LMNACYP2C9
SCHEMBL24734683 0.75 DPP4 (0.37) GPR119HRH3LMNACYP2C9
SCHEMBL23108661 0.75 GPR119 (0.36) GPR119HRH3LMNACYP2C9
SCHEMBL18950401 0.75 GPR119 (0.36) GPR119HRH3LMNACYP2C9TSHR
SCHEMBL28506728 0.75 GNAI3 (0.32)
SCHEMBL23103239 0.75 GPR119 (0.36) GPR119HRH3LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6768024-B1 CONTROLLING OBESITY, SEXUAL DYSFUNCTION OR INFLAMMATION LION BIOSCIENCE AG (DE) 2004-07-27 US claimed