SCHEMBL24734749

SCHEMBL24734749

C=Nc1cc(N)ccc1/C=C\C

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
F2 P00734 1/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
MAOA P21397 1/20 0.32
DRD1 P21728 1/20 0.32
ACHE P22303 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
KDR P35968 1/20 0.32
HTT P42858 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23656272 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL21499260 0.79 MAPT (0.36) LMNAADRA2AHTTKDM4EALDH1A1
SCHEMBL21648677 0.75 MAPT (0.37) MEN1KMT2AKCNH2KDM4EPOLB
SCHEMBL23731201 0.74
SCHEMBL22019510 0.74 CASP1 (0.44) LMNAMEN1F2CHRM2HTR1A
SCHEMBL13495488 0.74 CASP1 (0.44) LMNAMEN1F2CHRM2HTR1A
SCHEMBL16023620 0.74 HRH4 (0.36) PTGS1KDM4E
SCHEMBL14472177 0.73 PRKCI (0.39) LMNAMEN1ACHEPTGS1HTT
SCHEMBL14985583 0.73 LMNA (0.33) LMNAMEN1F2CHRM2HTR1A
SCHEMBL12810945 0.72 ALDH1A1 (0.50) LMNAMEN1KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4203661-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-06-28 EP disclosed
US-20230019732-A1 EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION 2023-01-19 US disclosed
EP-4099413-A1 COMPOSITION, LAYER INCLUDING THE COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019732-A1 EGFR INHIBITORS EGFR, ERBB2, ERBB3 LMNA 4685/4885MEN1 2867/4885F2 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.