Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 5/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24736556 | 0.85 | NOTUM (0.56) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24735946 | 0.85 | NOTUM (0.53) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24735966 | 0.83 | ROCK2 (0.51) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24736552 | 0.82 | ROCK2 (0.52) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24735950 | 0.78 | NOTUM (0.55) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24735985 | 0.78 | ROCK2 (0.66) | ROCK2ROCK1 | |
| SCHEMBL24736063 | 0.75 | IMPDH2 (0.54) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24736128 | 0.74 | NOTUM (0.54) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24736084 | 0.73 | ROCK1 (0.61) | ROCK2NOTUMPRMT3IMPDH2ROCK1 | |
| SCHEMBL24735962 | 0.72 | IMPDH2 (0.69) | ROCK2NOTUMPRMT3IMPDH2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389035-A1 | BORON-CONTAINING RHO KINASE INHIBITORS | PERCIPIAD, INC. | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389035-A1 | BORON-CONTAINING RHO KINASE INHIBITORS | ROCK1, ROCK2, RHOT2 | ROCK2 2/4885NOTUM 4314/4885PRMT3 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.