Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475270 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2891270 | 0.85 | MAPT (0.41) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2470643 | 0.83 | SCN4A (0.47) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2475625 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2475257 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL535781 | 0.79 | MAPT (0.44) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3912768 | 0.76 | PARP10 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2892781 | 0.75 | NR4A1 (0.49) | — | |
| SCHEMBL2891203 | 0.75 | MEN1 (0.41) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2473090 | 0.74 | RAF1 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370429-A1 | P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2011-10-05 | — | — | EP | disclosed |