Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vatiquinone SCHEMBL14639355 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| Vatiquinone SCHEMBL503125 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL13835534 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL2587312 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL6126503 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| Vatiquinone SCHEMBL502414 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL13836177 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL2591895 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| Vatiquinone SCHEMBL502413 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B | |
| SCHEMBL30132923 | 1.00 | ALOX15 (1.00) | ALOX15MAOBPTPN2PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293339-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | Stealth Bio Therapeutics Inc. (US) | 2024-09-05 | — | — | US | claimed |
| EP-4351547-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | Stealth BioTherapeutics Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| WO-2022261347-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-12-15 | — | — | WO | claimed |
| US-20240293339-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | Stealth Bio Therapeutics Inc. (US) | 2024-09-05 | — | — | US | disclosed |
| EP-4351547-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | Stealth BioTherapeutics Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261347-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022261347-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293339-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF VARIOUS MITOCHONDRIAL DISEASES OR DISORDERS, INCLUDING FRIEDREICH'S ATAXIA | AIFM2, FH, FECH | ALOX15 80/4885MAOB 2128/4885PTPN2 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.