Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721702 | 1.00 | LMNA (0.36) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL31244350 | 0.91 | LMNA (0.38) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736825 | 0.88 | KIT (0.37) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736806 | 0.83 | POLB (0.36) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736769 | 0.83 | KIT (0.37) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL29721751 | 0.83 | KIT (0.37) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL18866344 | 0.81 | POLB (0.42) | HTTSMN1; SMN2POLBGRIN1GRIN2B | |
| SCHEMBL24736768 | 0.81 | POLB (0.34) | POLBGRIN1GRIN2B | |
| SCHEMBL14684583 | 0.80 | POLB (0.48) | POLB | |
| SCHEMBL29360277 | 0.80 | POLB (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220361499-A1 | AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT EACH COMPRISING A CONDENSED HETEROCYCLIC COMPOUND HAVING A SUBSTITUTED CYCLOPROPANE-OXADIAZOLE GROUP OR A SALT THEREOF AS ACTIVE INGREDIENT, AND METHOD FOR USING THE INSECTICIDE OR THE CONTROL AGENT | NIHON NOHYAKU CO., LTD. (JP) | 2022-11-17 | — | — | US | disclosed |
| CN-114641475-A | Agricultural and horticultural insecticide or animal external or internal parasite control agent containing condensed heterocyclic compound having substituted cyclopropane oxadiazolyl group or salt thereof as active ingredient, and method for using same | 日本农药株式会社 | 2022-06-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220361499-A1 | AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT EACH COMPRISING A CONDENSED HETEROCYCLIC COMPOUND HAVING A SUBSTITUTED CYCLOPROPANE-OXADIAZOLE GROUP OR A SALT THEREOF AS ACTIVE INGREDIENT, AND METHOD FOR USING THE INSECTICIDE OR THE CONTROL AGENT | H1-3, H1-0, CBR3 | LMNA 3496/4885GAA 4245/4885HTT 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.