Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721751 | 0.91 | KIT (0.37) | POLBHSD11B1GRIN1GRIN2BHDAC1 | |
| SCHEMBL24736769 | 0.91 | KIT (0.37) | POLBHSD11B1GRIN1GRIN2BHDAC1 | |
| SCHEMBL24736768 | 0.89 | POLB (0.34) | POLBHSD11B1GRIN1GRIN2B | |
| SCHEMBL24737137 | 0.88 | HSD11B1 (0.34) | POLBHSD11B1GRIN1GRIN2BHDAC1 | |
| SCHEMBL31081668 | 0.87 | KIT (0.35) | POLB | |
| SCHEMBL31081418 | 0.86 | POLB (0.32) | POLBHSD11B1 | |
| SCHEMBL24736825 | 0.84 | KIT (0.37) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL29721702 | 0.83 | LMNA (0.36) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL24736788 | 0.83 | LMNA (0.36) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL18866344 | 0.82 | POLB (0.42) | POLBGRIN1GRIN2BHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220361499-A1 | AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT EACH COMPRISING A CONDENSED HETEROCYCLIC COMPOUND HAVING A SUBSTITUTED CYCLOPROPANE-OXADIAZOLE GROUP OR A SALT THEREOF AS ACTIVE INGREDIENT, AND METHOD FOR USING THE INSECTICIDE OR THE CONTROL AGENT | NIHON NOHYAKU CO., LTD. (JP) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220361499-A1 | AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT EACH COMPRISING A CONDENSED HETEROCYCLIC COMPOUND HAVING A SUBSTITUTED CYCLOPROPANE-OXADIAZOLE GROUP OR A SALT THEREOF AS ACTIVE INGREDIENT, AND METHOD FOR USING THE INSECTICIDE OR THE CONTROL AGENT | H1-3, H1-0, CBR3 | POLB 1781/4885CNR2 959/4885NR1H4 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.