Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24736788 | 1.00 | LMNA (0.36) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL31244350 | 0.91 | LMNA (0.38) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736825 | 0.88 | KIT (0.37) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736806 | 0.83 | POLB (0.36) | LMNAGAAHTTSMN1; SMN2POLB | |
| SCHEMBL24736769 | 0.83 | KIT (0.37) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL29721751 | 0.83 | KIT (0.37) | POLBGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL18866344 | 0.81 | POLB (0.42) | HTTSMN1; SMN2POLBGRIN1GRIN2B | |
| SCHEMBL24736768 | 0.81 | POLB (0.34) | POLBGRIN1GRIN2B | |
| SCHEMBL14684583 | 0.80 | POLB (0.48) | POLB | |
| SCHEMBL29360277 | 0.80 | POLB (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4029571-A1 | AGRICULTURAL AND HORTICULTURAL PESTICIDE HAVING AS ACTIVE COMPONENT CONDENSED HETEROCYCLIC COMPOUND HAVING SUBSTITUTED CYCLOPROPANE OXADIAZOLE GROUP OR SALT THEREOF; ECTOPARASITE OR ENDOPARASITE CONTROL AGENT FOR ANIMALS; AND USE METHOD THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2022-07-20 | — | — | EP | disclosed |
| CN-114641475-A | Agricultural and horticultural insecticide or animal external or internal parasite control agent containing condensed heterocyclic compound having substituted cyclopropane oxadiazolyl group or salt thereof as active ingredient, and method for using same | 日本农药株式会社 | 2022-06-17 | — | — | CN | disclosed |