Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556974 | 0.88 | TDP1 (0.44) | MAPK1LMNATSHRALDH1A1TP53 | |
| SCHEMBL3623562 | 0.84 | PARP1 (0.52) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL25295747 | 0.81 | UNG (0.55) | HPGDCYP1A2KDM4ETSHRALDH1A1 | |
| SCHEMBL7655031 | 0.80 | PARP1 (0.61) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL5488346 | 0.80 | PARP1 (0.61) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL27541340 | 0.79 | TSHR (0.55) | SMN1; SMN2TSHRALDH1A1TP53NPC1 | |
| SCHEMBL247378 | 0.79 | PARP1 (0.64) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| Acetic Acid SCHEMBL27798910 | 0.78 | SMN1; SMN2 (0.49) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL22734773 | 0.78 | PARP1 (0.53) | PARP1HPGDSMN1; SMN2GAANFKB1 | |
| SCHEMBL28999822 | 0.78 | HCRTR1 (0.41) | PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114920706-A | Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method | 新乡市润宇新材料科技有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-20200385328-A1 | METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-12-10 | — | — | US | disclosed |
| CN-108101856-B | Preparation method of acyl-substituted pyrazine compound | HENAN AGRICULTURAL UNIVERSITY (CN) | 2019-12-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385328-A1 | METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND | SDHA, FDPS, NDUFS5 | PARP1 1104/4885HPGD 26/4885SMN1; SMN2 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.