Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738163 | 0.90 | — | — | |
| SCHEMBL29302621 | 0.81 | — | — | |
| SCHEMBL24738969 | 0.78 | PTGS2 (0.31) | — | |
| SCHEMBL21355687 | 0.78 | TYK2 (0.31) | — | |
| SCHEMBL24737512 | 0.78 | — | — | |
| SCHEMBL24738161 | 0.78 | PPARA (0.32) | HTR4PTGER1 | |
| SCHEMBL29302622 | 0.77 | CTSS (0.33) | — | |
| SCHEMBL24738088 | 0.76 | KDM4E (0.34) | — | |
| SCHEMBL23571403 | 0.74 | HTR4 (0.32) | HTR4 | |
| SCHEMBL24738964 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022197758-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |