Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
| ▸ | ADH1C | P00326 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254246 | 0.98 | ALDH1A1 (0.38) | ADH1AADH1CALDH1A1HRH4HRH3 | |
| SCHEMBL15719057 | 0.91 | ALDH1A1 (0.39) | ADH1AADH1CALDH1A1 | |
| SCHEMBL3188510 | 0.82 | ALDH1A1 (0.46) | ADH1AALDH1A1ACHEBCHEPOLB | |
| SCHEMBL7805428 | 0.78 | ALDH1A1 (0.42) | ADH1AADH1CALDH1A1HRH4HRH3 | |
| SCHEMBL13677592 | 0.77 | BCHE (0.40) | ADH1AALDH1A1ACHEBCHEPOLB | |
| SCHEMBL24693692 | 0.76 | LMNA (0.38) | ADH1AADH1CALDH1A1ACHEBCHE | |
| SCHEMBL19718781 | 0.76 | SMYD3 (0.40) | ADH1AADH1CALDH1A1POLBKMT2A | |
| SCHEMBL24739060 | 0.76 | ACHE (0.43) | ALDH1A1ACHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL27952219 | 0.76 | LSS (0.35) | ADH1AADH1C | |
| SCHEMBL27866405 | 0.75 | KMT2A (0.37) | ADH1AADH1CALDH1A1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |