Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262943 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL14371725 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL15632175 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30680499 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL16857486 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30680515 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL15632464 | 0.88 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL14155394 | 0.84 | MMP2 (0.34) | — | |
| SCHEMBL7707939 | 0.83 | CHRM2 (0.39) | NR1H2CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL7712028 | 0.83 | CHRM2 (0.39) | NR1H2CHRM2CHRM1CHRM3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |