SCHEMBL24739626

O=C(NCC1CO1)c1cccc(-c2cccc(Oc3cc4c5c(cc(Oc6cccc(-c7cccc(C(=O)NCC8CO8)c7)c6)c6c7c(Oc8cccc(-c9cccc(C(=O)NCC%10CO%10)c9)c8)cc8c9c(cc(Oc%10cccc(-c%11cccc(C(=O)NCC%12CO%12)c%11)c%10)c(c3c56)c97)C(=O)N(C(Cc3ccncc3)C(=O)OCc3ccccc3)C8=O)C(=O)N(C(Cc3ccncc3)C(=O)OCc3ccccc3)COC4)c2)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	GPR132	Q9UNW8	1/20	0.33

▸	RAB9A	P51151	1/20	0.32

▸	ROCK2	O75116	2/20	0.32

▸	AURKA	O14965	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24739732	0.92	GPR132 (0.39)	GPR132RAB9AROCK2AURKA
SCHEMBL24740008	0.84	AURKA (0.35)	GPR132RAB9AROCK2AURKA
SCHEMBL24739612	0.83	AURKA (0.38)	GPR132RAB9AROCK2AURKA
SCHEMBL24739652	0.82	RAB9A (0.36)	GPR132RAB9AROCK2AURKA
SCHEMBL24739716	0.82	AURKA (0.37)	GPR132RAB9AROCK2AURKA
SCHEMBL24739843	0.82	AURKA (0.34)	GPR132RAB9AROCK2AURKA
SCHEMBL24739764	0.82	RAB9A (0.36)	GPR132RAB9AROCK2AURKA
SCHEMBL24739844	0.82	ALDH1A1 (0.36)	GPR132RAB9AROCK2AURKA
SCHEMBL24739873	0.81	AURKA (0.33)	GPR132RAB9AAURKA
SCHEMBL24739960	0.81	MAPT (0.36)	GPR132RAB9AAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220390841-A1	COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE	LG CHEM, LTD. (KR)	2022-12-08	—	—	US	disclosed