Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367965 | 0.84 | EPHX1 (0.48) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 | |
| SCHEMBL24112751 | 0.83 | PSEN1 (0.44) | EPHX1CHRNB2CHRNA4NAAAASAH1 | |
| SCHEMBL8393587 | 0.81 | EPHX1 (0.55) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 | |
| SCHEMBL24441491 | 0.81 | EPHX1 (0.50) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 | |
| SCHEMBL23836198 | 0.81 | NAAA (0.37) | NAAAASAH1SCN9ASCN5APSEN1 | |
| SCHEMBL8393585 | 0.80 | EPHX1 (0.58) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 | |
| SCHEMBL8392638 | 0.80 | EPHX1 (0.58) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 | |
| SCHEMBL25846419 | 0.78 | SCN9A (0.36) | ALDH1A1NAAAASAH1SCN9ASCN5A | |
| SCHEMBL27920617 | 0.77 | NAAA (0.37) | ALDH1A1NAAAASAH1SCN9ASCN5A | |
| SCHEMBL13967719 | 0.77 | EPHX1 (0.42) | ALDH1A1MEN1KMT2AEPHX1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | Pardes Biosciences, Inc. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | CTRL, CTSV, CTSL | ALDH1A1 2252/4885MEN1 4164/4885KMT2A 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.