SCHEMBL24740787

SCHEMBL24740787

Cc1nnccc1C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10297516 0.81 LMNA (0.31)
SCHEMBL26222594 0.74 TSHR (0.39)
SCHEMBL12777851 0.70
SCHEMBL8318455 0.70
SCHEMBL1179915 0.70 NOS3 (0.37)
SCHEMBL29770643 0.69
Hydrochloric Acid SCHEMBL28430002 0.67
Ammonia Solution, Strong SCHEMBL20338348 0.67
SCHEMBL29778866 0.67 NOS3 (0.39)
SCHEMBL27321293 0.67 HPGD (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022212819-A1 INDAZOLE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2022-10-06 WO disclosed