SCHEMBL24742467

SCHEMBL24742467

C=Cc1ccc(COc2ccc(-c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.56
APP P05067 1/20 0.56
DHFR P00374 1/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
NPC1 O15118 1/20 0.52
LMNA P02545 1/20 0.52
RAB9A P51151 1/20 0.52
CCR6 P51684 1/20 0.52
UBE2N P61088 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
NR4A2 P43354 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.49
MAOA P21397 1/20 0.49
PTPN1 P18031 1/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALOX5 P09917 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24742460 0.95 MAOB (0.61) MAOBAPPDHFRKMT2AKDM4E
SCHEMBL11903428 0.95 MAOB (0.61) MAOBAPPDHFRKMT2AKDM4E
SCHEMBL31453872 0.92 APP (0.48) APPNPC1RAB9APTPN1
SCHEMBL13242652 0.86 APP (0.54) MAOBAPPNPC1RAB9APTPN1
SCHEMBL6388039 0.86 APP (0.54) MAOBAPPNPC1RAB9APTPN1
SCHEMBL12459750 0.85 GSTP1 (0.58) MAOBAPPLMNARAB9AMAOA
SCHEMBL12885556 0.84 NPC1 (0.59) MAOBKMT2ANPC1RAB9AMAOA
SCHEMBL12650401 0.84 APP (0.56) MAOBAPPMAOASMPD1
SCHEMBL1480744 0.83 LMNA (0.55) MAOBKMT2AKDM4ELMNARAB9A
SCHEMBL8745237 0.81 HPGD (0.54) MAOBAPPKMT2AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022255606-A1 COMPOUND FOR QUANTUM DOT LIGHT EMITTING ELEMENT, QUANTUM DOT LIGHT EMITTING ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2022-12-08 WO disclosed