Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242652 | 0.91 | APP (0.54) | APPRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL6388039 | 0.91 | APP (0.54) | APPRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL11903428 | 0.86 | MAOB (0.61) | HPGDAPPRAB9ANPC1MAOB | |
| SCHEMBL24742460 | 0.86 | MAOB (0.61) | HPGDAPPRAB9ANPC1MAOB | |
| SCHEMBL31453872 | 0.85 | APP (0.48) | HPGDAPPRAB9ANPC1CASP3 | |
| SCHEMBL2849932 | 0.84 | APP (0.59) | APPRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL35299 | 0.82 | ALDH1A1 (0.58) | HPGDCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL1299394 | 0.82 | RAB9A (0.59) | HPGDAPPRAB9ANPC1CASP3 | |
| SCHEMBL18546472 | 0.82 | MAOB (0.61) | APPRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL21244006 | 0.82 | APP (0.61) | HPGDAPPRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5288758-A | Acetylcholinesterase inhibitors | PIERRE FABRE MEDICAMENT (FR) | 1994-02-22 | — | — | US | disclosed |
| US-5278267-A | Water insoluble vinyl aromatic polymer | EASTMAN KODAK COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| US-5210289-A | Homo or coploymers for medical diagnosis | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5149737-A | Carboxy group extended from polymer surface allows easier attachment of biological substances | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |