Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GNG2 | P59768 | 2/20 | 0.31 |
| ▸ | GNB1 | P62873 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25083068 | 0.75 | IMPDH2 (0.42) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL22951342 | 0.75 | NR4A2 (0.40) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL24742611 | 0.73 | MAPT (0.56) | IDO1NR4A2KDM4EHIF1ACYP3A4 | |
| SCHEMBL22951353 | 0.72 | IDO1 (0.38) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL24207461 | 0.71 | CYP2C19 (0.39) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL24207416 | 0.71 | IDO1 (0.35) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL22950952 | 0.69 | IDO1 (0.33) | IDO1NR4A2KDM4ECYP2C19HIF1A | |
| SCHEMBL3844688 | 0.68 | KDM4E (0.44) | IDO1KDM4ECYP2C19HIF1ACYP3A4 | |
| SCHEMBL20915738 | 0.68 | IDO1 (0.35) | IDO1NR4A2KDM4EHIF1ALMNA | |
| SCHEMBL116741 | 0.67 | ALDH1A1 (0.50) | IDO1NR4A2KDM4ECYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4105207-A1 | QUINOLYL PHOSPHINE OXIDE COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2022-12-21 | — | — | EP | disclosed |