Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744751 | 0.91 | CCNC (0.44) | EGFRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL24744345 | 0.90 | ALDH1A1 (0.41) | EGFRMAPTMAPKAPK2ALDH1A1KDM4E | |
| SCHEMBL24744068 | 0.90 | EGFR (0.48) | EGFRMAPTMAPKAPK2ALDH1A1KDM4E | |
| SCHEMBL24744391 | 0.89 | SLC6A4 (0.46) | EGFRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL24744753 | 0.89 | SLC6A3 (0.46) | EGFRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL24744328 | 0.88 | ALDH1A1 (0.41) | EGFRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL24744763 | 0.86 | NPC1 (0.51) | MAPTALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL24744771 | 0.86 | KDM4E (0.38) | EGFRMAPTMAPKAPK2ALDH1A1KDM4E | |
| SCHEMBL24744383 | 0.84 | KDM4E (0.42) | MAPTALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL24744331 | 0.84 | BRD4 (0.46) | EGFRMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347595-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | Council of Scientific & Industrial Research (IN) | 2024-04-10 | — | — | EP | claimed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | claimed |
| EP-4347595-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | Council of Scientific & Industrial Research (IN) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022254464-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AS METALLO-BETA-LACTAMASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-12-08 | — | — | WO | disclosed |