Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745449 | 0.84 | CACNA1B (0.40) | TLR7KDM4EGAAMAPTDCTPP1 | |
| SCHEMBL24745728 | 0.83 | ALDH1A1 (0.37) | TLR7KDM4EGAAMAPTDCTPP1 | |
| SCHEMBL24745532 | 0.82 | DCTPP1 (0.38) | TLR7KDM4EMAPTDCTPP1ALDH1A1 | |
| SCHEMBL24745467 | 0.82 | ALDH1A1 (0.37) | TLR7KDM4EGAAMAPTDCTPP1 | |
| SCHEMBL24744896 | 0.82 | KDM4E (0.36) | TLR7KDM4EGAAMAPTDCTPP1 | |
| SCHEMBL24745413 | 0.82 | BRD4 (0.38) | TLR7KDM4EGAAMAPTDCTPP1 | |
| SCHEMBL29893726 | 0.78 | PKN1 (0.47) | KDM4EGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24744762 | 0.78 | PKN1 (0.47) | KDM4EGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24745533 | 0.76 | PRMT5 (0.35) | TLR7KDM4EDCTPP1ALDH1A1CACNA1B | |
| SCHEMBL31090575 | 0.76 | PRMT5 (0.35) | TLR7KDM4EDCTPP1ALDH1A1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |