Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976992 | 0.88 | KMT2A (0.71) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL15044968 | 0.88 | MEN1 (0.54) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL11976994 | 0.87 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL19078689 | 0.87 | HPGD (0.54) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL19078686 | 0.85 | ALDH1A1 (0.56) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL12545839 | 0.83 | HPGD (0.63) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL21212584 | 0.81 | MGLL (0.49) | HSP90AA1HSP90AB1MEN1KMT2AHPGD | |
| SCHEMBL2655426 | 0.80 | KMT2A (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12546068 | 0.80 | HPGD (0.59) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL19185792 | 0.80 | HPGD (0.59) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |