Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713770 | 0.75 | NOS3 (0.41) | NOS3NOS2PIK3CAMTORALOX5AP | |
| SCHEMBL23485874 | 0.74 | — | — | |
| SCHEMBL3036428 | 0.73 | ALDH1A1 (0.44) | CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL16679463 | 0.72 | NOS3 (0.38) | NOS3NOS2PIK3CAMTORALOX5AP | |
| SCHEMBL2676833 | 0.72 | NOS3 (0.45) | NOS3NOS2PIK3CAMTORALOX5AP | |
| SCHEMBL29739395 | 0.72 | NOS3 (0.45) | NOS3NOS2PIK3CAMTORALOX5AP | |
| SCHEMBL24746460 | 0.72 | NOS3 (0.35) | NOS3NOS2PIK3CAMTOR | |
| SCHEMBL11465523 | 0.71 | HSD11B1 (0.39) | — | |
| SCHEMBL1692246 | 0.69 | SLC6A4 (0.41) | — | |
| SCHEMBL23361675 | 0.69 | NOS3 (0.38) | NOS3NOS2PIK3CAMTORALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |