⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811 | 0.78 | — | — | |
| SCHEMBL27985624 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL75527 | 0.78 | — | — | |
| SCHEMBL13445903 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL25474034 | 0.75 | — | — | |
| SCHEMBL4404375 | 0.75 | — | — | |
| SCHEMBL3890759 | 0.75 | — | — | |
| SCHEMBL3889888 | 0.75 | — | — | |
| SCHEMBL9157892 | 0.75 | LMNA (0.43) | — | |
| SCHEMBL437859 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195898-A1 | TREATMENT OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT USING GNRH-I ANALOGS AND ONE OR MORE OF ACETYLCHOLINESTERASE INHIBITORS AND NMDA RECEPTOR ANTAGONISTS | VOYAGER PHARMACEUTICAL CORPORATION (US) | 2011-08-11 | — | — | US | claimed |
| EP-1951719-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-08-06 | — | — | EP | claimed |
| US-20080171736-A1 | Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists | VOYAGER PHARMACEUTICAL CORPORATION | 2008-07-17 | — | — | US | claimed |
| WO-2007056469-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-4694874-A2 | GPX4 INHIBITORS AND SENOLYTIC COMPOUNDS AND USES THEREOF | Rubedo Life Sciences, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260007689-A1 | GPX4 Inhibitors and Senolytic Compounds and Uses Thereof | RUBEDO LIFE SCIENCES INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-12485132-B2 | GPX4 inhibitors and senolytic compounds and uses thereof | Rubedo Life Sciences, Inc. (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250319109-A1 | GPX4 Inhibitors and Senolytic Compounds and Uses Thereof | RUBEDO LIFE SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4541796-A1 | EXATECAN DERIVATIVES AND USE THEREOF | Hangzhou Adcoris Biopharma Co., Ltd (CN) | 2025-04-23 | — | — | EP | disclosed |
| US-20240408124-A1 | GPX4 Inhibitors and Senolytic Compounds and Uses Thereof | Rubedo Life Sciences, Inc. | 2024-12-12 | — | — | US | disclosed |
| US-4680409-A | CEPHALOSPORIN INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4610824-A | Hydrazide derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0177940-A2 | Hydrazine derivatives and their use | E.R. Squibb & Sons, Inc. (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4400517-A | PESTICIDES; APHIDICIDES; PARASITICIDES | MONTEDISON S.P.A. (IT) | 1983-08-23 | — | — | US | disclosed |
| US-4394387-A | INSECTICIDES, MITICIDES | THE BOOTS COMPANY PLC (GB) | 1983-07-19 | — | — | US | disclosed |
| US-4220789-A | CYCLIZATION OF A SEMICARBAZONE | MONTEDISON S.P.A. (IT) | 1980-09-02 | — | — | US | disclosed |
| US-4215196-A | Photographic elements in which gelatin silver halide layers contain polymers with semicarbazone or alkoxy carbonyl hydrazone groups | AGFA-GEVAERT N.V. (BE) | 1980-07-29 | — | — | US | disclosed |