SCHEMBL24747396

SCHEMBL24747396

CCCC1=C/C(=C2/C=C(C)C(=O)c3ccccc32)c2ccccc2C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.49
ALDH1A1 P00352 3/20 0.49
CDC25A P30304 2/20 0.49
CDC25B P30305 2/20 0.49
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 1/20 0.49
PLIN1 O60240 1/20 0.49
NR1I2 O75469 1/20 0.49
USP2 O75604 1/20 0.49
GSR P00390 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
GAA P10253 1/20 0.49
CYP2D6 P10635 1/20 0.49
HSPD1 P10809 1/20 0.49
CYP2C9 P11712 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24747397 0.92 PTPN1 (0.47) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL7140356 0.82 CDC25B (0.68) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL7146635 0.82 CDC25B (0.68) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL1137898 0.78 PTPN1 (0.56) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL18456446 0.74 CDC25B (0.46) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL13611379 0.70 PTPN1 (0.75) ALDH1A1CDC25BMAPTUSP2LMNA
SCHEMBL15893567 0.70 ALDH1A1 (0.52) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL27942011 0.69 CDC25B (0.49) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL18877805 0.69 MAPT (0.50) IDO1ALDH1A1CDC25ACDC25BMAPT
SCHEMBL27715900 0.68 PTPN1 (0.66) IDO1ALDH1A1CDC25ACDC25BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220397835-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-15 US disclosed