SCHEMBL24747397

SCHEMBL24747397

CCCC1=C/C(=C2/C=C(CCC)C(=O)c3ccccc32)c2ccccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.47
SOAT1 P35610 6/20 0.41
IDO1 P14902 2/20 0.41
CDC25B P30305 5/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 5/20 0.40
APAF1 O14727 2/20 0.40
LMNA P02545 5/20 0.40
MAPT P10636 5/20 0.40
S100A4 P26447 4/20 0.40
POLB P06746 3/20 0.40
HTT P42858 2/20 0.40
PTPRC P08575 2/20 0.40
USP2 O75604 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
PARK7 Q99497 1/20 0.40
MITF O75030 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
MAPK1 P28482 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24747396 0.92 IDO1 (0.49) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL1137898 0.85 PTPN1 (0.56) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL18456446 0.81 CDC25B (0.46) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL13611379 0.77 PTPN1 (0.75) PTPN1SOAT1CDC25BALDH1A1APAF1
SCHEMBL27942011 0.76 CDC25B (0.49) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL27715900 0.74 PTPN1 (0.66) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL17969811 0.73 PTPN1 (0.62) PTPN1CDC25BMEN1KMT2AALDH1A1
SCHEMBL8163726 0.73 PTPN1 (0.73) PTPN1SOAT1IDO1CDC25BMEN1
Ammonia Solution, Strong SCHEMBL28565537 0.73 PTPN1 (0.64) PTPN1SOAT1IDO1CDC25BMEN1
SCHEMBL14307223 0.73 CDC25B (0.50) PTPN1SOAT1IDO1CDC25BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220397835-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-15 US disclosed