Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009382 | 1.00 | CYP3A4 (0.50) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL10712987 | 0.84 | CYP3A4 (0.61) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL24110788 | 0.78 | ALOX5 (0.57) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL19921723 | 0.78 | CYP3A4 (0.54) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL8760214 | 0.77 | ACHE (0.48) | CYP3A4TUBB1 | |
| SCHEMBL27245311 | 0.77 | CA12 (0.45) | CYP3A4PTGS1TTR | |
| SCHEMBL19641869 | 0.75 | ALOX5 (0.64) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL4407650 | 0.75 | CYP3A4 (0.50) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL4399221 | 0.72 | PDE4A (0.47) | CYP3A4MAPTPTGS2ALOX5MAOB | |
| SCHEMBL4403722 | 0.72 | CYP3A4 (0.47) | CYP3A4MAPTPTGS2ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |