Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694827 | 1.00 | MAPK1 (0.56) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL31360509 | 0.86 | THRB (0.61) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL31694814 | 0.84 | THRB (0.52) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL24749780 | 0.84 | THRB (0.52) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL24749781 | 0.83 | L3MBTL1 (0.53) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL31694876 | 0.83 | L3MBTL1 (0.53) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6531818 | 0.83 | MAPK1 (0.75) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL10387449 | 0.82 | LMNA (0.68) | MAPK1TSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL31009451 | 0.81 | MAPT (0.67) | MAPK1TSHRSMN1; SMN2LMNATHRB | |
| SCHEMBL20554691 | 0.80 | THRB (0.53) | MAPK1TSHRSMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |