Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MVD | P53602 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149471 | 1.00 | KLK5 (0.43) | KLK5FKBP1AALDH1A1HSD17B10ROCK2 | |
| SCHEMBL14045138 | 0.85 | FKBP1A (0.45) | KLK5FKBP1AHSD17B10ROCK2SMN1; SMN2 | |
| SCHEMBL196944 | 0.85 | FKBP1A (0.45) | KLK5FKBP1AHSD17B10ROCK2SMN1; SMN2 | |
| SCHEMBL2606998 | 0.84 | ALDH1A1 (0.54) | KLK5FKBP1AALDH1A1MVDSMN1; SMN2 | |
| SCHEMBL23135776 | 0.84 | ALDH1A1 (0.54) | KLK5FKBP1AALDH1A1MVDSMN1; SMN2 | |
| SCHEMBL196943 | 0.84 | HSD17B10 (0.43) | KLK5FKBP1AHSD17B10ROCK2SMN1; SMN2 | |
| SCHEMBL18065823 | 0.84 | HSD17B10 (0.43) | KLK5FKBP1AALDH1A1HSD17B10ROCK2 | |
| SCHEMBL2115151 | 0.84 | HSD17B10 (0.43) | KLK5FKBP1AALDH1A1HSD17B10ROCK2 | |
| SCHEMBL7256996 | 0.84 | HSD17B10 (0.43) | KLK5FKBP1AHSD17B10ROCK2SMN1; SMN2 | |
| SCHEMBL7256995 | 0.84 | HSD17B10 (0.43) | KLK5FKBP1AHSD17B10ROCK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |