Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | BAD | Q92934 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28862925 | 0.98 | HSD17B1 (0.61) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6319718 | 0.89 | ALDH1A1 (0.66) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1304947 | 0.88 | HSD17B1 (0.66) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14020155 | 0.88 | PDE10A (0.58) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14020417 | 0.87 | HSD17B1 (0.64) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11989060 | 0.87 | HSD17B1 (0.60) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28901460 | 0.87 | HSD17B1 (0.60) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4088536 | 0.87 | HSD17B1 (0.68) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24621192 | 0.84 | SCD (0.61) | HSD17B1HSD17B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31407 | 0.84 | HSD17B1 (0.79) | HSD17B1HSD17B2RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120737084-A | Delta-sultone compound containing benzothiazole skeleton | 成都大学 | 2025-10-03 | — | — | CN | disclosed |
| CN-118271285-A | Azetidine-containing amide derivative, preparation method and application thereof | 贵州大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-115974867-A | Chiral phase transfer catalyst and preparation method and application thereof | 成都大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115551915-A | Polymerizable unsaturated group-containing alkali-soluble resin and method for producing same, and photosensitive resin composition and cured product thereof | 日铁化学材料株式会社 | 2022-12-30 | — | — | CN | disclosed |
| CN-110015985-B | 2- (alpha-deuterium-alpha-hydroxy-alpha-aryl/alkyl) aza-aromatic hydrocarbon compound and preparation method and application thereof | 河南师范大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-108906053-B | Hydrophobic hydrotalcite loaded bimetallic catalyst and oxidation catalysis application thereof | 中国科学院兰州化学物理研究所苏州研究院 | 2020-11-03 | — | — | CN | disclosed |
| US-9884839-B2 | Inhibitors of 17Beta-hydroxysteroid dehydrogenases type 1 and type 2 | ELEXOPHARM GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| EP-3089969-A2 | INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGENASES TYPE 1 AND TYPE 2 | Elexopharm GmbH (DE) | 2016-11-09 | — | — | EP | disclosed |
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | ELEXOPHARM GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |
| US-4592774-A | Herbicidal alpha heterocyclic carbinol carbamates, ureas and N-alpha-substituted acetylcarbamates | UNION CARBIDE CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| US-4477635-A | Polymeric triarylmethane dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4425338-A | INSECTICIDES, MITICIDES, APHIDICIDES | UNION CARBIDE CORPORATION (US) | 1984-01-10 | — | — | US | disclosed |
| US-4352804-A | ANTIULCER AGENTS, GASTROINTESTINAL DISORDERS | ACF CHEMIEFARMA NV (NL) | 1982-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318895-A1 | Inhibitors of 17Beta-Hydroxysteroid Dehydrogenases Type 1 and Type 2 | HSD17B1, HSD17B2, HSD17B3 | HSD17B1 1/4885HSD17B2 2/4885RAB9A 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.