SCHEMBL2475285

SCHEMBL2475285

C=CCC=C(C)C(=O)ONC(=O)OCC

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
GLO1 Q04760 1/20 0.33
GAA P10253 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 1/20 0.31
RAB9A P51151 1/20 0.31
MIF P14174 1/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410006 0.81 CYP2D6 (0.45) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL21483481 0.81 CYP2D6 (0.38) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL15564 0.80 ALDH1A1 (0.40) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL22126048 0.78 GLO1 (0.37) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL8665886 0.78 TSHR (0.35) ALDH1A1MAPT
SCHEMBL28299706 0.77 GLO1 (0.36) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL22493848 0.77 GLO1 (0.36) CYP2C19CYP2D6GLO1GAASMN1; SMN2
SCHEMBL26097613 0.77 GAA (0.43) CYP2C19CYP2D6GAASMN1; SMN2ALDH1A1
SCHEMBL21483476 0.76 FAAH (0.43) CYP2C19CYP2D6CYP1A2MAPT
SCHEMBL27647055 0.76 TSHR (0.33) GLO1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424219-B1 Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom DAICEL CHEM (JP) 1996-05-08 EP claimed
US-5143997-A Photo-curable or electron-beam curable coatings DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-01 US claimed
EP-0424219-A2 Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-24 EP claimed
EP-2373718-B1 GELCOAT COMPOSITION AND ARTICLES COMPRISING THE SAME SCOTT BADER CO (GB) 2014-08-13 EP disclosed
US-20110262755-A1 Gelcoat Composition and Articles Comprising the Same SCOTT BADER COMPANY LIMITED (GB) 2011-10-27 US disclosed
EP-2373718-A1 GELCOAT COMPOSITION AND ARTICLES COMPRISING THE SAME Scott Bader Company Limited (GB) 2011-10-12 EP disclosed
WO-2010073003-A1 GELCOAT COMPOSITION AND ARTICLES COMPRISING THE SAME SCOTT BADER COMPANY LIMITED (GB) 2010-07-01 WO disclosed
EP-0424219-B1 Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom DAICEL CHEM (JP) 1996-05-08 EP disclosed
US-5143997-A Photo-curable or electron-beam curable coatings DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-01 US disclosed
EP-0424219-A2 Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed