Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061302 | 0.94 | GNAO1 (0.42) | NCF1GNAO1GNAI3GNAI1HSD11B1 | |
| SCHEMBL22520648 | 0.91 | HRH3 (0.44) | GNAO1GNAI3GNAI1HSD11B1HRH3 | |
| SCHEMBL23603292 | 0.90 | NCF1 (0.39) | NCF1GNAO1GNAI3GNAI1HSD11B1 | |
| SCHEMBL14081460 | 0.89 | NCF1 (0.50) | NCF1GNAO1GNAI3GNAI1ACHE | |
| SCHEMBL22307041 | 0.88 | GNAO1 (0.47) | NCF1GNAO1GNAI3GNAI1ACHE | |
| SCHEMBL27267891 | 0.87 | NCF1 (0.48) | NCF1GNAO1GNAI3GNAI1HSD11B1 | |
| SCHEMBL27370368 | 0.85 | GNAO1 (0.50) | NCF1GNAO1GNAI3GNAI1HSD11B1 | |
| SCHEMBL7908231 | 0.83 | CYP1A2 (0.46) | GNAO1HSD11B1HRH3SMN1; SMN2 | |
| SCHEMBL12431826 | 0.83 | HSD11B1 (0.57) | HSD11B1 | |
| SCHEMBL3437028 | 0.83 | CYP1A2 (0.48) | NCF1GNAO1GNAI3GNAI1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |