Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25847142 | 0.88 | ATM (0.38) | ATMTRPA1KMT2AMEN1HSP90AA1 | |
| SCHEMBL21130456 | 0.80 | ATM (0.46) | ATMTRPA1KMT2AMEN1HSP90AA1 | |
| SCHEMBL22245540 | 0.79 | MEN1 (0.32) | ATMKMT2AMEN1HSP90AA1 | |
| SCHEMBL20406187 | 0.79 | CD44 (0.42) | ATMKMT2AMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL21651066 | 0.79 | POLB (0.37) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL20725206 | 0.79 | — | — | |
| SCHEMBL20406636 | 0.78 | GRIN2D (0.37) | ATMKMT2AMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL25801459 | 0.77 | GABRA1 (0.35) | ATMKMT2AMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL13779331 | 0.74 | MAPT (0.57) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL4350537 | 0.74 | ATM (0.43) | ATMTRPA1KMT2AMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401432-A1 | THERAPEUTIC METHODS, COMBINATIONS AND KITS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401432-A1 | THERAPEUTIC METHODS, COMBINATIONS AND KITS | MMP8, TLR7, GOT2 | ATM 3968/4885TRPA1 4779/4885KMT2A 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.