Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | DDO | Q99489 | 1/20 | 0.55 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933132 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL18041382 | 0.97 | KDM4E (0.66) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3400117 | 0.85 | SMN1; SMN2 (0.54) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL13279929 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1964003 | 0.79 | L3MBTL4 (0.69) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL14731492 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL24756635 | 0.78 | MEN1 (0.51) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL29224884 | 0.76 | HRH3 (0.50) | KDM4EALDH1A1MEN1KMT2AL3MBTL4 | |
| SCHEMBL18376152 | 0.76 | HPGD (0.64) | KDM4EALDH1A1KMT2AL3MBTL4L3MBTL3 | |
| SCHEMBL14991641 | 0.76 | L3MBTL3 (0.74) | KDM4EALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |