SCHEMBL24759751

SCHEMBL24759751

Cc1nc(Cc2ncnc3ccccc23)c2ccccc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.42
HTT P42858 4/20 0.41
LMNA P02545 4/20 0.41
EGFR P00533 3/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
TSHR P16473 4/20 0.40
RAB9A P51151 2/20 0.40
GALR3 O60755 2/20 0.40
NR2F2 P24468 2/20 0.40
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108399 0.78 EGFR (0.53) ADORA2AHTTLMNAEGFRPI4KA
SCHEMBL805510 0.75 POLB (0.54) HTTLMNAEGFRTSHRL3MBTL1
SCHEMBL14417174 0.74 LMNA (0.47) HTTLMNAEGFRTSHRL3MBTL1
SCHEMBL28062169 0.73 PDE4A (0.72) ADORA2AHTTLMNAEGFRPI4KA
SCHEMBL2614518 0.73 PI4KA (0.50) ADORA2AHTTLMNAEGFRPI4KA
SCHEMBL7067981 0.73 KDM4E (0.56) HTTLMNAPDE4APDE4BPDE4C
SCHEMBL13791538 0.72 PI4KA (0.40) ADORA2AHTTLMNAPI4KAPI4K2B
SCHEMBL16795425 0.71 PKM (0.54) HTTLMNAEGFRTSHRNPC1
SCHEMBL11953072 0.70 ALDH1A1 (0.48) ADORA2AHTTLMNAEGFRPI4KA
SCHEMBL27887765 0.70 CCNC (0.43) HTTLMNAEGFRPI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407027-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-22 US disclosed