Sugi Predict

Sugi Predict / Compounds / SCHEMBL2476047

SCHEMBL2476047

SCHEMBL2476047

C(#Cc1ccccc1)Oc1ccc(OC#Cc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.52
▸ FFAR1 O14842 1/20 0.44
▸ MAPT P10636 2/20 0.41
▸ CYP1A2 P05177 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ THPO P40225 1/20 0.39
▸ BLM P54132 1/20 0.38
▸ PMP22 Q01453 1/20 0.38
▸ GRM5 P41594 1/20 0.38
▸ CHRNB2 P17787 1/20 0.38
▸ CHRNB4 P30926 1/20 0.38
▸ CHRNA3 P32297 1/20 0.38
▸ CHRNA7 P36544 1/20 0.38
▸ CHRNA4 P43681 1/20 0.38
▸ CA12 O43570 2/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CA9 Q16790 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2190465 0.95 APP (0.52) APPFFAR1MAPTCYP1A2CYP3A4
SCHEMBL15827936 0.89 VCP (0.44) APPFFAR1MAPTCYP1A2CYP3A4
SCHEMBL15348783 0.89 APP (0.42) APPFFAR1MAPTCYP1A2CYP3A4
SCHEMBL13283920 0.89 LTA4H (0.48) APPFFAR1MAPTCYP1A2CYP2C19
SCHEMBL13283885 0.82 FFAR1 (0.37) APPFFAR1MAPTGRM5CHRNB2
SCHEMBL13283917 0.79 APP (0.41) APPFFAR1MAPTCYP1A2CYP3A4
SCHEMBL427752 0.76 CYP19A1 (0.44) APPFFAR1CYP1A2CYP3A4CYP2C9
SCHEMBL11330496 0.76 MAOB (0.53) APPFFAR1MAPTCYP1A2CYP3A4
SCHEMBL28516091 0.76 FFAR1 (0.45) APPFFAR1CYP3A4CHRNB2CHRNA4
SCHEMBL11330504 0.76 MAOB (0.48) FFAR1MAPTCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010086385-A9 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICALS AB (SE) 2010-10-07 — — WO claimed
WO-2010086385-A1 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICALS AB (SE) 2010-08-05 — — WO claimed
WO-2010087742-A1 ACETYLENIC AROMATIC POLYCARBONATE NEXAM CHEMICAL AB (SE) 2010-08-05 — — WO claimed
WO-2010074625-A1 ACETYLENIC AROMATIC POLYETHER NEXAM CHEMICAL AB (SE) 2010-07-01 — — WO claimed
WO-2010071532-A1 ACETYLENIC PHENOL-ALDEHYDE RESIN NEXAM CHEMICAL AB (SE) 2010-06-24 — — WO claimed
WO-2010030216-A1 ACETYLENIC POLY(ALKYLENE PHTHALATE) NEXAM CHEMICAL AB (SE) 2010-03-18 — — WO claimed
EP-2373721-B1 ACETYLENIC AROMATIC POLYETHERKETONE NEXAM CHEMICAL AB (SE) 2014-06-25 — — EP disclosed
EP-2391666-B1 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICAL AB (SE) 2013-08-28 — — EP disclosed
EP-2373721-A1 ACETYLENIC AROMATIC POLYETHERKETONE Nexam Chemical AB (SE) 2011-10-12 — — EP disclosed
WO-2010086385-A9 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICALS AB (SE) 2010-10-07 — — WO disclosed
WO-2010086385-A1 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICALS AB (SE) 2010-08-05 — — WO disclosed
WO-2010087742-A1 ACETYLENIC AROMATIC POLYCARBONATE NEXAM CHEMICAL AB (SE) 2010-08-05 — — WO disclosed
WO-2010074625-A1 ACETYLENIC AROMATIC POLYETHER NEXAM CHEMICAL AB (SE) 2010-07-01 — — WO disclosed
WO-2010072760-A1 ACETYLENIC AROMATIC POLYETHERKETONE NEXAM CHEMICAL AB (SE) 2010-07-01 — — WO disclosed
WO-2010071532-A1 ACETYLENIC PHENOL-ALDEHYDE RESIN NEXAM CHEMICAL AB (SE) 2010-06-24 — — WO disclosed
WO-2010030216-A1 ACETYLENIC POLY(ALKYLENE PHTHALATE) NEXAM CHEMICAL AB (SE) 2010-03-18 — — WO disclosed