Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476047 | 0.95 | APP (0.52) | APPMAPTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL15348783 | 0.85 | APP (0.42) | APPMAPTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL15827936 | 0.85 | VCP (0.44) | APPMAPTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL13283920 | 0.85 | LTA4H (0.48) | APPMAPTFFAR1CYP1A2CYP2C19 | |
| SCHEMBL9421959 | 0.81 | LTA4H (0.50) | APPTSHRLTA4HKCNA3ALDH1A1 | |
| SCHEMBL28516091 | 0.80 | FFAR1 (0.45) | APPFFAR1CYP3A4TSHRLTA4H | |
| SCHEMBL427752 | 0.80 | CYP19A1 (0.44) | APPFFAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11330504 | 0.80 | MAOB (0.48) | MAPTFFAR1CYP3A4ALDH1A1KDM4E | |
| SCHEMBL11330496 | 0.80 | MAOB (0.53) | APPMAPTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL13283917 | 0.79 | APP (0.41) | APPMAPTFFAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1643030-A | Low dielectric constant materials and methods of preparation thereof | HONEYWELL INT INC (US) | 2005-07-20 | — | — | CN | claimed |
| US-3939278-A | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-02-17 | — | — | US | claimed |
| CN-113248511-B | Synthesis method of pyrano [2,3-b ] quinoline alkaloid | 常州大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113248511-A | Synthesis method of pyrano [2,3-b ] quinoline alkaloid | 常州大学 | 2021-08-13 | — | — | CN | disclosed |
| US-9493436-B2 | Tyrosine phosphatase inhibitors and uses thereof to modulate the activity of enzymes involved in the pathology of Mycobacterium tuberculosis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| US-9108930-B2 | N1- and N2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140179735-A1 | TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF TO MODULATE THE ACTIVITY OF ENZYMESp INVOLVED IN THE PATHOLOGY OF MYCOBACTERIUM TUBERCULOSIS | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2014-06-26 | — | — | US | disclosed |
| US-20140018318-A1 | N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS | THE SCIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
| US-8524847-B2 | Organic insulating material, varnish for resin film using the same, resin film and semiconductor device | SUMITOMO BAKELITE CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| EP-2157107-B1 | ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE CO (JP) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012149048-A1 | TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF TO MODULATE THE ACTIVITY OF LYP | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2012-11-01 | — | — | WO | disclosed |
| US-20090318610-A1 | ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES | SUMITOMO BAKELITE CO., LTD (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2117009-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |
| CN-1643030-A | Low dielectric constant materials and methods of preparation thereof | HONEYWELL INT INC (US) | 2005-07-20 | — | — | CN | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0670856-A1 | THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012556-A2 | THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |
| US-3939278-A | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
| US-3939278-A | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
| US-3939278-A | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018318-A1 | N1- and N2-CARBAMOYL-1,2,3-TRIAZOLE SERINE HYDROLASE INHIBITORS AND METHODS | PRSS1, PRSS3, CES1 | APP 1376/4885MAPT 4098/4885FFAR1 3487/4885 |
| US-20140179735-A1 | TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF TO MODULATE THE ACTIVITY OF ENZYMESp INVOLVED IN THE PATHOLOGY OF MYCOBACTERIUM TUBERCULOSIS | PPP3CB, PPP4C, PTPRB | APP 2247/4885MAPT 2475/4885FFAR1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.